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5A-1MQ-treated mice switched from WD to LD (WD/LD-T) showed a rather reduced relative abundance of Akkermansia compared to vehicle-treated DIO animals switched from WD to LD (WD/LD-V), suggesting a unique microbiome mechanism associated with weight loss in the vehicle-treated group switched from WD to LD compared to the 5A-1MQ-treated group that underwent the same diet switch
This is because GH is an anabolic hormone that plays an important role in muscle growth, and CJC-1295 has a proven ability to increase levels of GH in test subjects
Refer to the MHRA for UK medicines regulation.
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